If The choice is produced to prescribe a benzodiazepine or other CNS depressant concomitantly with an opioid analgesic, prescribe the lowest effective dosages and minimum durations of concomitant use. In patients already obtaining an opioid analgesic, prescribe a lower initial dose with the benzodiazepine or other CNS depressant than indicated https://codeine.store/codeine-and-alcohol/