The role of common fragile sites (CFSs) in cancer remains controversial. Two main views dominate the discussion: one suggests that CFS loci are hotspots of genomic instability leading to inactivation of genes encoded within them. while the other view proposes that CFSs are functional units and that loss of the encoded genes confers selective pressure. leading to cancer development. https://www.pyrodresoners.shop/product-category/vtx-and-vrx-accessories/