ABCB1/P-glycoprotein is an ATP binding cassette transporter that is involved in the clearance of xenobiotics. and it affects the disposition of many drugs in the body. Conformational flexibility of the protein within the membrane is an intrinsic part of its mechanism of action. but this has made structural studies challenging. https://www.rivervalleydanceac.com/product-category/autographed-framed-entertainment-items-other/